Of these loci, DRD2 is notable as a long-studied addiction candidate gene4 and its recent identification as genome-wide significant for alcohol use disorder for rs493627767, which is correlated (r2 = 0.94 in 1000 G EUR, 0.82 in 1000 G AFR) with rs7125588, the top SNP identified for CPD in GSCAN and associated with ND in iNDiGO; these results support a shared genetic effect of DRD2 underlying addiction. Here, DRD2 is linked to alcohol abuse.