The genetic correlation between ND and gene expression in cerebellum is a notable observation consistent with cerebellum-specific cis-eQTL effects observed for the ND-associated DNMT3B SNP rs91008322 and the age of smoking initiation-associated CHRNA2 SNP rs1178047136, both of which are also associated with lung cancer. The gene discussed is CHRNA2; the disease is lung carcinoma.