KMT2A and leukemia: Starting from a verified set of 128 upregulated lncRNAs from our previous microarray study [28], we first identified that the gene loci of 47 lncRNAs were marked by H3K27ac (Additional file 1: Table S1), a histone mark of active enhancers (as assessed by ChIP-seq data from the MLL leukemia cell line MV4-11), indicating that these lncRNAs might act as lnc-eRNAs.