The Alzheimer’s disease PGS with the APOE region included was marginally associated with the odds of dementia relative to normal cognition only for the pT cutoff of 0.01 (OR = 1.1 95%CI 1.0 to 1.2), while the Alzheimer’s disease PGS at all other P-value thresholds was not significantly associated with the odds of dementia. Here, APOE is linked to dementia.