To further demonstrate the regulatory role of Hdac3 on Pgf expression in BPD mice via the miR-17-EZH1-p65 axis in vivo, hyperoxia + Hdac3−/− + miR-17-antagomir mice were constructed through injection of miR-17 antagomir into hyperoxia + Hdac3−/− mice. The gene discussed is RELA; the disease is bronchopulmonary dysplasia.