Previous literature has reported that Hdac3 participated in the remodeling and expansion of distant alveolar vesicles into primitive pulmonary alveolus by downregulating the miR-17-92 cluster (Wang et al. 2016), which commonly constitutes to the occurrence of BPD in premature infants (Ruiz-Camp et al. 2019). The gene discussed is HDAC3; the disease is bronchopulmonary dysplasia.