Pgf is a member of the vascular endothelial growth factor (VEGF) family of angiogenesis regulators and the molecular structure is glycoprotein homodimer; higher plasma VEGF/Pgf levels have been found in preterm neonates with BPD and in those who died before 28 days of life, indicating an important role of this substance in pulmonary vascular development (Procianoy et al., 2016). The gene discussed is VEGFA; the disease is bronchopulmonary dysplasia.