The level of U-FABP4 was independently associated with levels of proteinuria and eGFR in patients with kidney disease, and the association of U-FABP4 with proteinuria or eGFR was independent of circulating FABP4 and U-FABP1, which reflects damage of proximal tubular epithelial cells [16, 17]. The gene discussed is FABP4; the disease is kidney disorder.