The over-production is particularly evident for IL6 and IL8 whose effects in IPF onset have been already identified [34,35]; G-CSF is another overexpressed cytokines and it is involved in the production and maturation of granulocytes [36], including macrophages that are the predominant cell type among the inflammatory ones in the lung after agent-induced IPF in mice [37]. The gene discussed is CXCL8; the disease is idiopathic pulmonary fibrosis.