In this series, it was found that the 6-year-old girl with RI, PS, and mesenteric adenopathy and was colonized by Pseudomonas aeruginosa had hypercupremia, iron deficiency, and slightly high CRP; the 9-year-old girl with RS and PI and was colonized by Hemophilus influenzae had hypercupremia; the 15-year-old male with PI and RS and was colonized by Aspergillus fumigatus had hypocupremia, prealbumin deficiency, and lymphopenia (1610 cell/mm3). This evidence concerns the gene CRP and Iron deficiency anemia.