Likewise, plasma Ud-OPN was significantly (p < 0.0001) higher in AIDS (median: 123 ng/mL), TB (median: 65·1 ng/mL), and AIDS/TB (median: 103 ng/mL) patients, compared with the control (median: 8·34 ng/mL) (Figure 4A). The gene discussed is SPP1; the disease is tuberculosis.