SRSF1 and breast cancer: Additionally, among splicing regulators frequently altered in breast cancers (in >5% of tumors [35]), we found different members of SR protein family (such as SRSF1, SRSF2, SRSF3, SRSF4, SRSF6, SRSF9, SRSF10, SRSF11) with at least one predicted binding motif in the CD44 v10 region (Table S2).