ESR1 and neoplasm: In particular, CD163+ macrophages positively correlate with higher grade, larger tumor size, Ki67 positivity, estrogen receptor negativity, progesterone receptor negativity, and TNBC/BLBC subtypes, and inversely correlate with the luminal A subtype, while CD68+ macrophages correlate with tumor size and inversely correlate with the luminal A subtype [136].