KCNH2 and torsades de pointes: In 2005, the Council on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use suggested principles for checking new molecules for the risk of inducing potentially fatal arrhythmias (e.g., torsade the points (TdP)) caused by blocking the human Ether-à-go-go-Related Gene (hERG, KV11.1) [17,18].