Currently, there are separate scoring systems for PD-L1 staining in NSCLC tumour cells with four FDA-approved PD-L1 assays (antibodies: 22C3, 28.8, SP263 and SP142) on two different platforms (Dako, Ventana) [68,69,70,71,72]. This evidence concerns the gene CD274 and non-small cell lung carcinoma.