To understand this topic fully, serum concentrations of other neuroactive mediators and markers of multiple sclerosis, such as serum neurofilament light, tumor necrosis factor α, interleukin 1β, neutralizing antibodies against interferon beta, and the analysis of oligoclonal bands and other markers in cerebrospinal fluid, could have been monitored. The gene discussed is NEFL; the disease is multiple sclerosis.