Several studies have demonstrated the coagulation abnormalities in COVID-19 patients to be characterized as [88,89] (a) elevation of FDPs such as D-Dimer, (b) modestly elevated PT, (c) mostly normal or slightly depressed PTT, (d) variable variations in platelet counts, (e) elevated levels of fibrinogen, von Willebrand factor and factor VIII levels and (f) normal levels of factor XIa. The gene discussed is VWF; the disease is COVID-19.