Consistent with this, a report has shown inadequate levels of PD-1 on T cells and PD-L1 on myeloid (m) DCs in the peripheral blood of CAD patients, demonstrating a strong stimulant nature of CAD mDCs to activate T cells that are further accompanied with IFN-γ and IL-2 cytokine production. This evidence concerns the gene CD274 and coronary artery disorder.