Interestingly, the ectopic expression of miR-409 in normal prostate fibroblasts conferred a cancer-associated stroma-like phenotype and the release of this miRNA via exosomes was able to promote tumorigenesis and epithelial-mesenchymal transition (EMT) through repression of Ras suppressor 1 (RUS1) and stromal antigen 2 (STAG2) [31]. Here, STAG2 is linked to cancer.