MINDY4 and neoplasm: To evaluate whether FAM188B could be a potential target for controlling tumor growth, A549 cells that were transfected with either NC siRNA or siFAM188B for 48 h were subcutaneously injected in mice (n = 10) and tumor growth was monitored as illustrated in Figure 6A. Compared with the NC siRNA-treatment group, the siFAM188B-treated group showed significantly retarded tumor growth rate.