The DNA copy number of FAM188B was significantly increased in lung adenocarcinoma and squamous cell lung carcinoma compared with that in normal blood and lungs in TCGA lung 2 (https://www.oncomine.org/resource/ui/component/dataset.html?component=d:156636501) and Weiss lung cancer dataset (https://www.oncomine.org/resource/ui/component/dataset.html?component=d:156636653) [26] with a threshold of p < 0.0001 (Figure 7B and Figure S5). This evidence concerns the gene MINDY4 and lung adenocarcinoma.