The other cytokines, hormones or growth factors, and micro ribonucleic acids are also involved in the pathophysiology of PCOS, such as vascular epithelial growth factor (VEGF), tumor necrosis factor alpha (TNF-α), interleukin (IL), adipocytokine family (chemerin, omentin-1, leptin, adiponectin, and others), leptin, differentially expressed in normal and neoplastic development (DENND), RAS-related protein 5b (RAB5B), and small noncoding micro ribonucleic acid (microRNAs, miRNAs, and miR), including miR-130b-3p [68,71,73]. Here, LEP is linked to polycystic ovary syndrome.