Of note, the presence of tumor-derived microRNAs in both tissues and body fluids offers an opportunity for their potential application as liquid biopsy-based biomarkers, and future studies should evaluate whether emerging circulating microRNAs could be a useful tool for minimally-invasive estimation of hENT-1 levels and prediction of gemcitabine activity in PDAC patients. Here, SLC29A1 is linked to neoplasm.