The following predictors were associated with worse prognosis in all age, sex and health status subgroups: dyspnoea, unspecified comorbidity, cardiovascular disease, hypertension, diabetes, kidney disease, pulmonary disease and cancer, lymphocytes, leukocytes, neutrophils and platelets count, D-dimer, prothrombin time, AST, urea nitrogen, creatinine, C-reactive protein, Interleukine-6, LDH and procalcitonin. The gene discussed is F2; the disease is cardiovascular disorder.