CD34 and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss: Our data indicate that there is a specific stromal cell adaptive response rather than just a general increase in all stromal cells because we showed that cells expressing CD34/GP38 (Figure 6), which have niche activity in mice (22, 24), were not expanded in intestinal biopsies from human subjects with SBS.