The albumin/creatinine ratio (expressed as mg albumin: mmol creatinine; ACR) is a sensitive indicator of kidney disease, and patients are classified according to the 2012 guidelines developed by the Kidney Disease: Improving Global Outcomes organization (KDIGO) [52] as: normal < 3 mg/mmol (A1), moderate 3–30 mg/mmol (A2), severe > 30 mg/mmol (A3; nephropathy). This evidence concerns the gene ALB and kidney disorder.