HMGB1 and osteosarcoma: Certain noncoding RNAs (i.e., microRNA 22 [miRNA‐22])174 and drugs (i.e., 3,4‐dihydroxy‐9,10‐secoandrosta‐1,3,5,7‐tetraene‐9,17‐dione)175 enhance the sensitivity of osteosarcoma cells to chemotherapy by inhibiting HMGB1‐induced autophagy; therefore, HMGB1 plays an important role in the occurrence, progression, and sensitivity of osteosarcoma to chemotherapy.