APOB and colorectal carcinoma: Therefore, leveraging the serum lipid measurements in approximately 400,000 participants in the UK Biobank, we conducted a prospective cohort study to investigate the associations between lipid profiles (HDL, LDL, TC, TG, apolipoprotein A (ApoA) and apolipoprotein B (ApoB)) and risk of CRC, independent of other established and suspected risk factors.