Thus, while on week 7 post infection (pi), 30% (6/20) of the animals were already positive with total IgG, IgG1, the most abundant subclass was only elevated in 3/20 dogs and IgG2 and IgG3 levels were over the cut-off value in 5% and 10% of the animals, respectively. This evidence concerns the gene IGHG3 and infection.