MALAT1 and posterior cortical atrophy: The PCa cells have similar responses to Cis and Carboplatin treatment, with 0.2 μg/ml of Cis or 5 μg/ml Carboplatin suppressing Malat1 expression, 1 μg/ml of Cis or 10 μg/ml Carboplatin decreasing AR/ARv7 protein expression by ~50%, and 2 μg/ml of Cis or 20 μg/ml Carboplatin could trigger the apoptotic pathway (Fig. 3g).