TLR3 and autoimmune pancreatitis: Several AIP-like experimental models have been induced in transgenic mice inoculating microbial agents: C57BL/6 mice infected with the murine leukemia retrovirus LP-BM5, developed histological findings similar to human AIP [81,82]; in MRL/Mp mice the administration of polyinosinic:polycytidylic acid (poly I:C), a synthetic double-stranded RNA and TLR3 ligand, promotes the development of AIP-like pancreatitis [83,84,85,86].