Accordingly, increased numbers of mitotic ECs (i.e. co-expression of Ki-67 and ERG Birdsey et al., 2015; Booth and Earnshaw, 2017) were seen for cavernomas, but not in the pseudo-normal vessels of the Pdcd10-ko brain (Figure 4D, representative immunofluorescence; Figure 4E, quantification; Video 1). Here, MKI67 is linked to cavernous hemangioma.