PML and cancer: In addition to STAT3 and p53, NEAT1 has been shown to be regulated by other cancer-related transcription factors, such as HIF-2α (Choudhry et al., 2015), Oct4 (Jen et al., 2017), PML/RARA (Zeng et al., 2014), and c-Myc (Zeng et al., 2018).