Comparative proteome analysis of human and mouse CMD samples as well as pairwise matching of identified chemokines and their cognate receptors allowed us to identify few common chemotactic axes, including CXCL7/CXCL1,2,3-CXCR2 and CCL2-CCR2, as potential gradients for targeting of ADSC into CMD muscles. Here, CXCR2 is linked to congenital muscular dystrophy.