Analysis of human and mouse CMD-affected muscles revealed a number of upregulated chemokines that could play an important role in CMD pathology and that CCL5-CCR1/3/5, CCL2-CCR2, and CXCL1/2/7/8-CXCR1,2 chemotaxis axes could be used for the targeting of therapeutic cells to the injured CMD muscles. The gene discussed is CXCL1; the disease is congenital muscular dystrophy.