Carriers of one or at least one polymorphic IL1B rs16944 allele were also less likely to develop PCOS (OR = 0.49; 95% CI = 0.27–0.86; p = 0.014 and OR = 0.54; 95% Cl = 0.31–0.92; p = 0.024, respectively). This evidence concerns the gene IL1B and polycystic ovary syndrome.