MTNR1B and type 2 diabetes mellitus: Moreover, we had two additional secondary aims as follows: (2) To extend these results and to analyze the association of the MTNR1B- s10830963 polymorphism on fasting glucose and on prevalent type-2 diabetes risk in two elderly populations (replication cohorts); and (3) To retrospectively explore the influence of the number of full-term pregnancies on the risk of type-2 diabetes conferred by the MTNR1B polymorphism in one of the replication cohorts where this information was available.