MTNR1B and obesity due to melanocortin 4 receptor deficiency: We observed that in the stratified analysis by sex, the p-values for the interaction term between the MTNR1B-rs10830963 polymorphism (as additive) and age (dichotomous in 41 years) determining fasting glucose concentrations in the fully adjusted model including age, type-2 diabetes, and obesity were: p = 0.021 for men and p = 0.032 for women.