XIAP and breast cancer: [42,73]; (2) Elevated expression levels of XIAP were positively related to resistance to chemotherapy and radiotherapy [67,74]; (3) In addition, XIAP is implicated to modulate tumor cells resistance to immunotherapy, with evidence showing that XIAP is responsible for antibody-dependent cellular cytotoxicity in caspase-dependent and -independent mechanisms in inflammatory breast cancer cells [75].