Considering that there is no adequate treatment or drug that would act on the cause of the AD, the inhibition of human cholinesterases (acetylcholinesterase, AChE, EC 3.1.1.7; and butyrylcholinesterase, BChE, EC 3.1.1.8) emerged as an important therapeutic regime [3,4,5,6,7,8]. The gene discussed is ACHE; the disease is Alzheimer disease.