Specifically, the same missense SNP in the ATP binding cassette subfamily B member (TAP2) gene, rs2228391 (p = 5.1 × 10−3, OR = 377.7, 95% CI 5.93–24028), as observed here at a higher frequency in MIA cases was previously associated with susceptibility of a northern Chinese Han population to antithyroid drug-induced agranulocytosis [53]. Here, TAP2 is linked to Absence of circulating granulocytes.