BBC3 and neoplasm: Even if the tumor seemed significantly increased compared to benign glands for PUMA (p = 0.0043, average MFI = 1129 for benign and 1180 for tumor) and NOXA (p < 0.0001, average MFI = 247 for benign and 272 for tumor), the differences between each average expression were very similar (Figure 2A,B, respectively).