We found that, compared to women with a PRAL score, women with a higher PRAL score were more likely to be younger, overweight and obese; had a higher range of depression scores; and higher intakes of vitamin B12 and lower intakes of vegetables; they were less likely to be postmenopausal women and tamoxifen users and have positive ER or PR status. This evidence concerns the gene PGR and depressive disorder.