In univariable Cox proportional hazard analysis, age, gender (male), ischemic heart disease, atrial fibrillation, MBP, hemoglobin, eGFR, sodium, blood urea nitrogen, log CRP, log BNP, history of HF, diuretics, log GNRI and log TCBI were associated with the all-cause mortality (Table 2a). This evidence concerns the gene NPPB and coronary artery disorder.