In both pediatric age groups specific factors, including tumor necrosis factor (TNF)α, eotaxin, insulin-like growth factor (IGF)-1, leptin, triglycerides (TGL), monocyte chemeoattractant protein (MCP)1 and brain derived neurotrophic factor (BDNF), were identified as biomarkers involved in insulin resistance. The gene discussed is CCL2; the disease is Insulin resistance.