This includes lissencephaly (TUBA1A), polymicrogyria (TUBA1A, TUBB2B, TUBB3), microcephaly (TUBB2B, TUBB3, TUBB5, TUBG1), and oculomotor disorders (TUBB2B, TUBB3) [1,11–14]. The gene discussed is TUBB3; the disease is lissencephaly spectrum disorders.