We found significant differences in terms of BALF levels of CXCL9, CXCL10, CCL3, Fas-L, IL-6, IL-8, and IL-18 between the CVD–ILD, IPAF, and IPF groups (CXCL9; 11.1, 5.8, and 3.0 pg/ml, CXCL10; 99.0, 102.8, and 37.8 pg/ml, CCL3; 8.0, 5.2, and 3.7 pg/ml, Fas-L; 0.7, 1.6, and 0.5 pg/ml, IL-6; 0.5, 0.5, and 0.1 pg/ml, IL-8; 157.4, 97.0, and 48.5 pg/ml, IL-18; 12.4, 12.3, and 4.5 pg/ml). This evidence concerns the gene CXCL8 and interstitial lung disease.