CXCL9, CXCL10, and CXCL11 are involved in the pathogenesis of CVD–ILD and ILD as follows: In patients with PM/DM and SSc, the serum CXCL10 levels are higher in patients with ILD than in those without ILD [19, 20]. This evidence concerns the gene CXCL11 and systemic sclerosis.