Thus, similar to other genetic diseases, including cystic fibrosis [104] and von Hippel-Lindau disease [105], as well as certain cancer-linked mutations in p53 [106], it may be possible to stabilize some misfolded FLCN protein variants using a small molecule that either blocks the PQC system or directly stabilizes the FLCN protein structure [107]. Here, FLCN is linked to von Hippel-Lindau disease.