However, there are few comparative or switch studies available to confirm this hypothesis.10–13 While it needs to be explored, it is possible that T1D patients who use isCGM but continue to have a poor glycemic control despite using isCGM (severe hypoglycemia, chronic hyperglycemia) might benefit from rtCGM rather than modifying their insulin management while still preserving their comfort and autonomy. The gene discussed is INS; the disease is type 1 diabetes mellitus.