AD brain endothelial cells express high levels of inflammatory adhesion molecules, such as monocyte chemoattractant protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1), and cationic antimicrobial protein 37 kDa (CAP37) (Frohman et al. 1991; Pereira et al. 1996; Grammas and Ovase 2001). This evidence concerns the gene CCL2 and Alzheimer disease.