Additionally,high levels of WEE1 expression have been observed in the event ofsevere DNA stress in various cancer types correlating with a poorprognosis.109,110 The cancer types that highlyexpress WEE1 are thought to be extremely reliant on the G2 haltingof the cell cycle, making them an attractive target for WEE1 inhibition. The gene discussed is WEE1; the disease is cancer.