CD14 increases in plasma during the first 24 hr after sepsis initiation and remains elevated at least during the first 8 days, conferring an exceptional long-term prognostic value over acute phase proteins or IL-6 that quickly decrease after 3–8 days of sepsis (Behnes et al., 2014; Martínez-García et al., 2019). The gene discussed is IL6; the disease is Sepsis.