Although one study of nondiabetic, nonobese patients with genotype 1 (G1) chronic hepatitis C (CHC) showed that serum RBP4 level was positively linked to viral steatosis and CHC patients had higher RBP4 levels than the controls [19], other CHC studies either failed to link RBP4 positively with steatosis [11,20], or demonstrated a lower RBP4 level than the controls [11]. The gene discussed is RBP4; the disease is cryohydrocytosis.