A total of 680 TCGA RNA‐s Equation (TCGA‐seq) samples and 281 CGGA RNA‐s Equation (CGGA‐seq) samples were evaluated to investigate the relation between mRNA expression of BET family members BRD2/BRD3/BRD4, and overall survival (OS) in glioma patients. This evidence concerns the gene BRD2 and central nervous system cancer.