In addition to binding directly to SARS‐CoV‐2 genome, both datasets indicate that miR‐15b‐5p potentially induces T‐cell exhaustion by repressing the expression of IFNG and CD69. 23, 24These evidences suggest a key role for miR‐15b‐5p in COVID‐19 pathogenesis and patient deterioration. The gene discussed is CD69; the disease is COVID-19.