The frequency of TERTp mutations in our study was 62.6%, which is lower than that of previous reports from North America and European countries, which reported mutation frequencies of 73%–75% in IDH wild-type GBMs.3–5 Other reports from Japan also showed relatively low frequencies of TERTp mutations among IDH wild-type GBM, ranging from 50% to 70%.6,9,29 Thus, racial differences in the frequency of TERTp mutations may exist. This evidence concerns the gene IDH1 and glioblastoma.